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Shrew Venom Solutions

Shrew looks like a mouse with a long, pointed nose, but it is not a rodent but one of the few poisonous mammals. Shrews mainly eat insects, which are numerous and widely distributed. Many shrew species are poisonous and do not have fangs like poisonous snakes, but there is a gland that allows the venom to flow with the saliva, giving it an advantage when it encounters the prey. At present, only the venom of Blarina brevicauda shrew has been analyzed, and it is confirmed that the main toxic component is shrew toxin.

The toxins produced by common venomous animals such as spiders, snakes, and scorpions have been characterized, while the venom of venomous mammals has not been fully studied, such as shrews. Creative Proteomics uses comprehensive molecular methods to research and identify shrew venom, and provides customers with shrew venom solutions to explore whether it has medical and therapeutic uses.

Our Shrew Venom Solutions

We purify and characterize the shrew venom, analyze the characteristics and toxicity of the venom, conduct further functional analysis of the newly discovered toxin, and complete the comprehensive characterization of this venom system.

Shrew Venom Solutions

Service Areas

Unlike most mammals, some species of shrews are poisonous. We provide venom research solutions for toxic shrew species, including but not limited to the following specific species:

  • Neomys fodiens
  • Hispaniolan solenodon S. paradoxus
  • Neomys milleri
  • Crocidura canarienis
  • Sorex cinereus
  • Sorex palustris
  • Scutisorex somereni
  • Notiosorex crawfordi
  • Talpa europaea
  • Chimarrogale platycephalus
  • S. cubanus
  • B. brevicauda
  • S. thori

Sample Requirements

Sample Type Sample Form Vessel Storage Conditions Protein Concentration
Shrew submandibular gland Tissue homogenate Aseptic container -80 ℃ frozen 1 μg/μl
Shrew saliva Saliva Aseptic container -80 ℃ frozen 1 μg/μl

If you cannot provide the above samples directly, we can help you with sample collection and preparation, in accordance with the animal experiment management plan and the permission of the ethics committee.

Advantages

  • High precision. The long-read sequence and short-read data in the genome data are mutually verified, which has higher accuracy.
  • High throughput. LC/MS analysis found a large number of venom proteins in the saliva proteome.
  • High integrity. Complete analysis of samples and comprehensive information storage.

Creative Proteomics has a wealth of venom research experience, including a wide range of toxic animals. We provide specialized solutions and have many successful cases. If you need research services on the venom of a specific toxic species, please contact us.

Reference

  • Hanf Z R and Chavez A S. A Comprehensive Multi-Omic Approach Reveals a Relatively Simple Venom in a Diet Generalist, the Northern Short-Tailed Shrew, Blarina brevicauda. Genome Biology and Evolution, 2020, (7):7.
For research use only. Not intended for any clinical use.
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