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STEM Analysis Service

STEM (short for the Short Time-series Expression Miner) is a Java program for clustering, comparing, and visualizing short time series gene expression data from microarray experiments (~8 time points or fewer). Data from short time series gene expression experiments poses special challenges. In these experiments, thousands of genes are being profiled at the same time while the number of time points is few. In such cases, a lot of genes will have the same expression pattern just by random chance. Moreover as with any time series experiment, there are usually few full time series repeats from which to gain statistical power. Now, scientists at Creative Proteomics are proud to offer our customers STEM Analysis Service.

The features and advantages of STEM analysis

STEM uses a method of analysis that make use of the number of genes being large and the number of time points being few to identify statistically significant temporal expression profiles and the genes related to these profiles.
This method also supports Gene Ontology (GO) enrichment analysis for sets of genes with the same temporal expression pattern providing the means for a statistic allyrigorous biological interpretation of significant temporal expression patterns.
The integration of STEM with GO is bidirectional. STEM can easily identify and visualize the behavior of genes belonging to a specific GO category, determining which expression profiles were enriched for genes in that category.
Eventually, STEM also supports the comparation of temporal responses of genes across experimental conditions.

How to place an order:
How To Place your Order

*If your organization requires signing of a confidentiality agreement, please contact us by email

As one of the leading omics industry company in the world! Creative Proteomics now is opening to provide STEM analysis service for our customers. With rich experience in the field of bioinformatics, we are willing to provide our customer the most outstanding service! Contact us for all the detailed informations!

* For Research Use Only. Not for use in diagnostic procedures.

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From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

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Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

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