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Molecular Mass Determination Service

Information of molecular mass and distribution can help you to understand the composition, properties, and identity of your protein sample. Our molecular weight analysis techniques include Mass Spectrometry (MS), offering accuracy of measurement over a wide molecular weight range, with minimal amount of sample. With our well-established platform, we promise accurate identification and monitoring of low intensity isoforms. Furthermore, any difference between theoretical and measured mass may be identified as potential modifications on the proteins.

Our comprehensive service and detailed reports will provide you with the number average molecular weight (Mn), weight average molecular weight (Mw), z-average molecular weights (Mz) and Polydispersity (Mw/Mn) on both single and multi-component polymer samples.

List of our molecular mass determination service:

Number average molecular weight (Mn)
Weight average molecular weight (Mw)
Z-average molecular weights (Mz)
Polydispersity (Mw/Mn) on both single and multi-component polymer samples
Accurate molecular mass determination service (proteins with modifications, such as glycosylation, phosphorylation, etc.)
Molecular mass distribution service

Molecular mass determination

Technology platforms:

Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Gel permeation chromatography (GPC)
Size exclusion chromatography (SEC)
Matrix Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS)
Electrospray Ionization Mass Spectrometry (ESI-MS)
Liquid Chromatography with Mass Spectrometry Detection (LC-MS)

Feature and advantage of our molecular mass determination service:

Intact protein molecular weight characterization
Compatible for a wide range of molecules – peptides, proteins, glycoproteins
Accurate mass measurement – clarification of the elemental composition of molecules
Strictly follow ICH Q6B requirements for characterization of biopharmaceuticals
Quality control and SOP-driven wokflow

Ordering Procedure:

Ordering Procedure

Proteomics Sample Submission Guidelines

Ensure your samples are prepared and submitted correctly by downloading our comprehensive Proteomics Sample Submission Guidelines. This document provides detailed instructions and essential information to facilitate a smooth submission process. Click the link below to access the PDF and ensure your submission meets all necessary criteria.

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* For Research Use Only. Not for use in diagnostic procedures.

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From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

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