Submit Your Request Now

Cholesterol Ester Analysis Service

Cholesterol esters are a dietary lipid, which derived from cholesterol. Cholesterol esters are formed when the body produces enzymes to produce a metabolic reaction with the cholesterol itself. The ester bond is formed between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Cholesterol esters are largely spread in body fluids of animals (plasma lipoproteins) and may be also found in vessel walls as fatty streaks in atherosclerosis. Cholesterol esters have a lower solubility in water due to their increased hydrophobicity.

For the analysis of cholesterol esters, we use a MS protocol that yields profiling data on all individual cholesterol ester molecular species based on the associated fatty acids. We recommend cholesterol ester profiling scans at the semi-quantitative level, which allows direct comparison between samples or treatments. On special request, we can also quantitate the molecular species based on existing standards.

Technology Platform:

ESI Liquid Chromatography Mass Spectrometry (ESI- LC/MS)

Sample Type:

Cultured Cells
Cultured or uncultured primary mouse cells or cell lines

Cholesterol esters could monitored in This Service
14:0 CHOLESTERYL ESTER	15:0 CHOLESTERYL ESTER	16:0 CHOLESTERYL ESTER
16:1 CHOLESTERYL ESTER	17:0 CHOLESTERYL ESTER	18:0 CHOLESTERYL ESTER
18:1 CHOLESTERYL ESTER	18:2 CHOLESTERYL ESTER	18:3 CHOLESTERYL ESTER
20:0 CHOLESTERYL ESTER	20:4 CHOLESTERYL ESTER	22:0 CHOLESTERYL ESTER
22:4 CHOLESTERYL ESTER	22:6 CHOLESTERYL ESTER	More on request

Ordering Procedure:

Ordering Procedure

With integrated set of separation, characterization, identification and quantification systems featured with excellent robustness & reproducibility, high and ultra-sensitivity, Creative Proteomics provides reliable, rapid and cost-effective Lipidomics services.

Lipidomics Sample Submission Guidelines

Download our Lipidomics Sample Preparation Guide for essential instructions on proper sample collection, storage, and transport for optimal experimental results. The guide covers various sample types, including tissues, serum, urine, and cells, along with quantity requirements for untargeted and targeted lipidomics.

Download

Metabolomics Sample Submission Guidelines

* For Research Use Only. Not for use in diagnostic procedures.

Our customer service representatives are available 24 hours a day, 7 days a week. Inquiry

From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

Great Minds Choose Creative Proteomics