Multi-Channel Phosphorylated Protein Analysis Service
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Service Details
Protein phosphorylation, a reversible post-translational modification (PTM) in various organisms, plays a key role in the regulation of signal transduction, transcriptional and translational regulation, and the regulation of intracellular biological processes such as metabolism. The study of protein phosphorylation helps to understand life activities and helps to elucidate the mechanism of diseases related to abnormal protein phosphorylation.
Mass spectrometry (MS) is a promising tool for analyzing protein phosphorylation, capable of analyzing thousands of proteins in a single analysis. However, it is necessary to enrich phosphorylated peptides to improve the abundance of modified proteins before quantitative analysis of phosphorylated protein samples by quantitative proteomics analysis due to the low content and wide dynamic range of phosphorylated proteins in biological samples. Currently, a variety of enrichment techniques, including immunoprecipitation (IP), chemical modification, immobilized metal affinity chromatography (IMAC), and metal oxide affinity chromatography (MOAC), have been developed and applied to study phosphorylation of different biological samples.
Fig.1. Different strategies of phosphopeptide enrichment. (Li X S, et al., 2016)
With a powerful mass spectrometry sequencing platform and multi-pathway enrichment kit, Creative Proteomics pushs out a multi-pathway phosphorylated proteome analysis platform, a complement to phosphorylated protein analysis, to help you understand phosphorylation more easily.
At Creative Proteomics, our specialists use the multi-pathway enrichment kit to enrich phosphorylated peptides prior to mass spectrometry analysis. Compared with other phosphopeptide enrichment methods, multi-pathway enrichment kit enrichment is easy to operate and enables large-scale analysis of phosphorylated proteins.
With cutting-edge equipment and expertise in protein sequencing and mass spectrometry, we provide one-stop multi-pathway phosphorylated protein analysis service. You only need to tell us the purpose of your experiment and send your samples to us, we will take care of all the follow-up matters of the project. The simple process of our service includes:
Thanks to our powerful mass spectrometry sequencing platform, Creative Proteomics provides a one-stop multi-channel hosphorylated rotein analysis service. Our experienced scientists work with you to develop tailor-made analytical solutions. Please feel free to contact us with any questions regarding multi-channel hosphorylated rotein analysis.
References
For research use only, not intended for any clinical use.