Blood Proteomics
Blood, a dynamic and accessible biofluid, contains a diverse array of proteins that play crucial roles in various physiological functions. Blood proteomics is the systematic study of proteins in blood, providing a window into the complex molecular structure of the circulatory system. With rich experience, Creative Proteomics offers high-quality blood proteomics services, providing valuable insights into your protein research.
What is Blood Proteomics
The blood proteome, a comprehensive catalog of proteins circulating in the bloodstream, serves as a rich source of information about the physiological state of an individual. The blood proteome consists of a wide array of proteins with diverse functions, including enzymes, transporters, hormones, cytokines, clotting factors, and antibodies. Changes in the blood proteome reflect the dynamics of various biological processes. Studying the blood proteome holds immense potential for diagnosing diseases, understanding immune responses, and identifying biomarkers indicative of health or pathology.
Fig.1 Schematic of blood proteomics
In recent years, advancements in high-throughput technologies, such as mass spectrometry and immunoassays, have revolutionized the study of the blood proteome. Researchers are now able to analyze large datasets to identify and quantify proteins in blood samples with unprecedented accuracy. Large-scale data analysis and the integration of multi-omics approaches have enabled researchers to map the complex network of proteins in the blood, expanding the understanding of the blood proteome and deciphering their role in health and disease.
Applications of Blood Proteomics
Medical Diagnosis
Screening for disease biomarkers in the blood advances early screening and prevention of diseases, and helps in the diagnosis of diseases such as cancer, cardiovascular diseases and infectious diseases.
Clinical Research
Understanding the dynamics of the blood proteome in various physiological states can help provide insight into the molecular mechanisms of disease and therapeutic effects.
Personalized Medicine
Blood is a dynamic window into the body's physiological state, and tailoring interventions based on individual differences in the blood proteome contributes to the development of personalized medicine.
Translational Research
Blood proteomics bridges the gap between basic science discoveries and clinical applications, contributing to the understanding of physiological processes and driving research translation.
Our Service
With advanced protein detection technology, Creative Proteomics provides targeted solutions for researchers and scientists to help them utilize powerful analytical techniques to reveal the complexity of the proteome. With our thoughtful and detailed services, you can choose any protein analysis, including qualitative, quantitative, targeted and PTM analysis, and we will provide you with a detailed plan according to your requirements. The blood proteomics service process is as follows:
Fig.2 Blood proteomics workflow
- Sample Preparation
Obtaining a blood sample from an organism is the basis of this analysis, and the blood sample needs to be well preserved and protected from contamination prior to analysis. - Extraction
Separating and extracting proteins from blood is essential for blood proteomics, and it is essential to remove high-abundance proteins in order to more comprehensively examine the blood proteome. - Detection
WB, protein microarrays and LC-MS/MS are powerful tools for the identification and quantification of peptides, and they provide detection information that facilitates a comprehensive analysis of the blood proteome. - Bioinformatics Analysis
The raw mass spectrometry data undergoes bioinformatics analysis to identify proteins, quantify their abundance, and infer potential functional roles. - Result Delivery
After professional data analysis, we deliver results quickly and consistently.
Creative Proteomics brings a wealth of experience to the field of protein research. Our comprehensive services and products cover the entire spectrum of utilizing suitable and efficient gateways. Utilizing our proprietary platform, we have successfully implemented many proteomics research projects. If you are interested, please contact us for more information and a quote.