DNA-based Tumor Suppressor Genes

Oncogenes and tumor suppressor genes can cause malignant transformation of cells when they are mutated, deleted or inactivated, leading to tumorigenesis. Therefore, studying the molecular mechanism of tumorigenesis and development, and exploring oncogenes and tumor suppressor genes and their signaling pathways in different tumors and their subtypes can provide molecular markers for early diagnosis of tumors and molecular targets for drug development. Therefore, the research of oncogenes and tumor suppressor genes has important theoretical and clinical significance.

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